A high-fat diet impairs reproduction by decreasing the IL1β level in mice treated at immature stage

Abstract Obesity causes low-grade inflammation that is involved in male infertility. Interleukin 1 beta (IL1β) plays an important role in this process. A high-fat diet (HFD) is the most common cause of obesity. However, the effect of a HFD on IL1β and its consequence in reproduction remain unclear....

Full description

Bibliographic Details
Main Authors: Jie Zhang, kai Li, Miao Yuan, Guizen Huang, Jie Ao, Haoze Tan, Yanyan Li, Di Gong, Jun Li, lei Kang, Nini An, Fei Li, Ping Lin, Lugang Huang
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00505-0