Cancer Outlier Analysis Based on Mixture Modeling of Gene Expression Data

Molecular heterogeneity of cancer, partially caused by various chromosomal aberrations or gene mutations, can yield substantial heterogeneity in gene expression profile in cancer samples. To detect cancer-related genes which are active only in a subset of cancer samples or cancer outliers, several m...

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Bibliographic Details
Main Authors: Keita Mori, Tomonori Oura, Hisashi Noma, Shigeyuki Matsui
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:Computational and Mathematical Methods in Medicine
Online Access:http://dx.doi.org/10.1155/2013/693901