Comparative EPR Study on the Scavenging Effect of Methotrexate with the Isomers of Its Photoswitchable Derivative

Comparative EPR Study on the Scavenging Effect of Methotrexate with the Isomers of Its Photoswitchable Derivative

The scavenging effect of the antimetabolite dihydrofolate reductase inhibitor methotrexate (MTX) and the isomers of its photoswitchable derivate, <i>cis</i>- and <i>trans</i>-phototrexate (PHX), have been compared by ESR spectroscopy, with the application of a cyclic hydroxyl...

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Bibliographic Details
Main Authors: Zsolt Preisz, Nóra Hartvig, Balázs Bognár, Tamás Kálai, Sándor Kunsági-Máté
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Pharmaceuticals
Subjects:
methotrexate
phototrexate
photopharmacology
photoswitchable
electron paramagnetic resonance (EPR)
scavenger
Online Access:https://www.mdpi.com/1424-8247/14/7/665

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https://www.mdpi.com/1424-8247/14/7/665

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