Guanidinoacetate alters antioxidant defenses and butyrylcholinesterase activity in the blood of rats

Guanidinoacetate alters antioxidant defenses and butyrylcholinesterase activity in the blood of rats

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Deficiency of guanidinoacetate methyltransferase, the first described creatine biosynthesis defect, leads to depletion of creatine and phosphocreatine, and accumulation of guanidinoacetate (GAA) in brain and body fluids. The present study aimed to investigate the influence of GAA on the activities o...

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Bibliographic Details
Main Authors: Guilherme André Eger, Vinícius Vialle Ferreira, Camila Ribeiro Batista, Daniela Delwing de Lima, Angela Terezinha de Souza Wyse, Júlia Niehues da Cruz, Débora Delwing Dal Magro, José Geraldo Pereira da Cruz
Format: Article
Language:English
Published: Hospital de Clinicas de Porto Alegre ; Universidade Federal do Rio Grande do Sul (UFRGS) 2015-03-01
Series:Clinical and Biomedical Research
Subjects:
Butyrylcholinesterase
glutathione
guanidinoacetate
L-NAME
TBARS
trolox
Online Access:http://seer.ufrgs.br/index.php/hcpa/article/view/52197

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http://seer.ufrgs.br/index.php/hcpa/article/view/52197

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