Age-Related Changes in the Hepatic Pharmacology and Toxicology of Paracetamol

Optimal pharmacotherapy is determined when the pharmacokinetics and pharmacodynamics of the drug are understood. However, the age-related changes in pharmacokinetics and pharmacodynamics, as well as the increased interindividual variation mean optimal dose selection are a challenge for prescribing i...

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Bibliographic Details
Main Authors: Sarah J. Mitchell, Alice E. Kane, Sarah N. Hilmer
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Current Gerontology and Geriatrics Research
Online Access:http://dx.doi.org/10.1155/2011/624156