Efficient computation of spaced seed hashing with block indexing
Abstract Background Spaced-seeds, i.e. patterns in which some fixed positions are allowed to be wild-cards, play a crucial role in several bioinformatics applications involving substrings counting and indexing, by often providing better sensitivity with respect to k-mers based approaches. K-mers bas...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-11-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-018-2415-8 |