Efficient computation of spaced seed hashing with block indexing

Abstract Background Spaced-seeds, i.e. patterns in which some fixed positions are allowed to be wild-cards, play a crucial role in several bioinformatics applications involving substrings counting and indexing, by often providing better sensitivity with respect to k-mers based approaches. K-mers bas...

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Bibliographic Details
Main Authors: Samuele Girotto, Matteo Comin, Cinzia Pizzi
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-018-2415-8