Toward a humanized mouse model of Pneumocystis pneumonia

Pneumocystis is an important opportunistic fungus that causes pneumonia in children and immunocompromised individuals. Recent genomic data show that divergence of major surface glycoproteins may confer speciation and host range selectivity. On the other hand, immune clearance between mice and humans...

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Bibliographic Details
Main Authors: Guixiang Dai, Alanna Wanek, Taylor Eddens, Paul Volden, Jay K. Kolls
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-01-01
Series:JCI Insight
Subjects:
Online Access:https://doi.org/10.1172/jci.insight.139573