Investigation of ‘Head-to-Tail’-Connected Oligoaryl N,O-Ligands as Recognition Motifs for Cancer-Relevant G-Quadruplexes

Oligomeric compounds, constituted of consecutive N,O-heteroaromatic rings, introduce useful and tunable properties as alternative ligands for biomolecular recognition. In this study, we have explored a synthetic scheme relying on Van Leusen oxazole formation, in conjunction with C–H activation of th...

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Bibliographic Details
Main Authors: Natalia Rizeq, Savvas N. Georgiades
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/22/12/2160