Yeast Cth2 protein represses the translation of ARE-containing mRNAs in response to iron deficiency.
In response to iron deficiency, the budding yeast Saccharomyces cerevisiae undergoes a metabolic remodeling in order to optimize iron utilization. The tandem zinc finger (TZF)-containing protein Cth2 plays a critical role in this adaptation by binding and promoting the degradation of multiple mRNAs...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-06-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC6023232?pdf=render |