Targeting cancer stem cells for reversing therapy resistance: mechanism, signaling, and prospective agents
Abstract Cancer stem cells (CSCs) show a self-renewal capacity and differentiation potential that contribute to tumor progression and therapy resistance. However, the underlying processes are still unclear. Elucidation of the key hallmarks and resistance mechanisms of CSCs may help improve patient o...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-02-01
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Series: | Signal Transduction and Targeted Therapy |
Online Access: | https://doi.org/10.1038/s41392-020-00430-1 |