CD4+CD38+ central memory T cells contribute to HIV persistence in HIV-infected individuals on long-term ART

CD4+CD38+ central memory T cells contribute to HIV persistence in HIV-infected individuals on long-term ART

Abstract Background Despite the effective antiretroviral treatment (ART) of HIV-infected individuals, HIV persists in a small pool. Central memory CD4+ T cells (Tcm) make a major contribution to HIV persistence. We found that unlike HLA-DR, CD38 is highly expressed on the Tcm of HIV-infected subject...

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Bibliographic Details
Main Authors: Cheng-Bo Song, Le-Le Zhang, Xian Wu, Ya-Jing Fu, Yong-Jun Jiang, Hong Shang, Zi-Ning Zhang
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
HIV
Reservoir
CD38
Tcm
CD4+ T cell
Online Access:http://link.springer.com/article/10.1186/s12967-020-02245-8

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http://link.springer.com/article/10.1186/s12967-020-02245-8

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