Inhibition of triple negative breast cancer metastasis and invasiveness by novel drugs that target epithelial to mesenchymal transition

Abstract Invasive breast cancer (BrCa) is predicted to affect 1 in 9 women in a lifetime;1 in 32 will die from this disease. The most aggressive forms of BrCa, basal-like/triple-negative phenotype (TNBC), are challenging to treat and result in higher mortality due high number of metastatic cases. Th...

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Bibliographic Details
Main Authors: Elizabeth Garcia, Ismat Luna, Kaya L. Persad, Kate Agopsowicz, David A. Jay, Frederick G. West, Mary M. Hitt, Sujata Persad
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91344-7