Emergence and propagation of epistasis in metabolic networks
Epistasis is often used to probe functional relationships between genes, and it plays an important role in evolution. However, we lack theory to understand how functional relationships at the molecular level translate into epistasis at the level of whole-organism phenotypes, such as fitness. Here, I...
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Format: | Article |
Language: | English |
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eLife Sciences Publications Ltd
2021-02-01
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Series: | eLife |
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Online Access: | https://elifesciences.org/articles/60200 |