DOCK8 Immune Deficiency as a Model for Primary Cytoskeletal Dysfunction

DOCK8 deficiency is a newly described primary immune deficiency resulting in profound susceptibility to cutaneous viral infections, elevated IgE levels, and eosinophilia, but lacking in the skeletal manifestations commonly seen in hyper IgE syndrome, which it otherwise resembles. Although little is...

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Bibliographic Details
Main Authors: Sean A. McGhee, Talal A. Chatila
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.3233/DMA-2010-0740