Cerebrospinal fluid PKR level predicts cognitive decline in Alzheimer's disease.

Cerebrospinal fluid PKR level predicts cognitive decline in Alzheimer's disease.

The cerebrospinal fluid (CSF) levels of the proapoptotic kinase R (PKR) and its phosphorylated PKR (pPKR) are increased in Alzheimer's disease (AD), but whether CSF PKR concentrations are associated with cognitive decline in AD patients remain unknown. In this study, 41 consecutive patients wit...

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Bibliographic Details
Main Authors: Julien Dumurgier, Francois Mouton-Liger, Pauline Lapalus, Magali Prevot, Jean-Louis Laplanche, Jacques Hugon, Claire Paquet, Groupe d’Investigation du Liquide Cephalorachidien (GIL) Study Network
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3539966?pdf=render

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http://europepmc.org/articles/PMC3539966?pdf=render

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