Microglia P2X4 receptor contributes to central sensitization following recurrent nitroglycerin stimulation

Microglia P2X4 receptor contributes to central sensitization following recurrent nitroglycerin stimulation

Abstract Background The mechanism underlying migraine chronification remains unclear. Central sensitization may account for this progression. The microglia P2X4 receptor (P2X4R) plays a pivotal role in the central sensitization of inflammatory and neuropathic pain, but there is no information about...

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Bibliographic Details
Main Authors: Ting Long, Wei He, Qi Pan, Shanshan Zhang, Yixin Zhang, Chaoyang Liu, Qing Liu, Guangcheng Qin, Lixue Chen, Jiying Zhou
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Journal of Neuroinflammation
Subjects:
P2X4R
Microglia
Migraine
Nitroglycerin
Animal model
Online Access:http://link.springer.com/article/10.1186/s12974-018-1285-3

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http://link.springer.com/article/10.1186/s12974-018-1285-3

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