Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
Physical features of the extracellular matrix (ECM) heavily influence cell migration strategies and efficiency. Migration in and on fibrous ECMs is of significant physiologic importance, but limitations in the ability to experimentally define the diameter, density, and alignment of native ECMs in vi...
Main Authors: | William Y. Wang, Alexander T. Pearson, Matthew L. Kutys, Colin K. Choi, Michele A. Wozniak, Brendon M. Baker, Christopher S. Chen |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2018-12-01
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Series: | APL Bioengineering |
Online Access: | http://dx.doi.org/10.1063/1.5052239 |
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