Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration

Physical features of the extracellular matrix (ECM) heavily influence cell migration strategies and efficiency. Migration in and on fibrous ECMs is of significant physiologic importance, but limitations in the ability to experimentally define the diameter, density, and alignment of native ECMs in vi...

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Bibliographic Details
Main Authors: William Y. Wang, Alexander T. Pearson, Matthew L. Kutys, Colin K. Choi, Michele A. Wozniak, Brendon M. Baker, Christopher S. Chen
Format: Article
Language:English
Published: AIP Publishing LLC 2018-12-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/1.5052239