Effect of Ginsenoside Rg1 on the intervertebral disc degeneration rats and the degenerative pulposus cells and its mechanism

Objective: To explore the effect of ginsenoside Rg1 on intervertebral disc degeneration (IVDD) in vivo and in vitro and its mechanism. Methods: 60 rats were underwent surgery to construct rat models of IVDD and divided in the sham group, model group and gradient G-Rg1 groups (10 mg/kg/d, 20 mg/kg/d...

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Bibliographic Details
Main Authors: Lei Yu, Yingjie Hao, Cheng Peng, Panke Zhang, Jian Zhu, Yingchun Cai, Guangduo Zhu
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219353600