Mycobacterium leprae Induces Neutrophilic Degranulation and Low-Density Neutrophil Generation During Erythema Nodosum Leprosum

Mycobacterium leprae Induces Neutrophilic Degranulation and Low-Density Neutrophil Generation During Erythema Nodosum Leprosum

Erythema Nodosum Leprosum (ENL) is a recurrent acute inflammatory complication of leprosy affecting up to 50% of all Borderline Lepromatous and Lepromatous Leprosy (BL/LL) patients. Although ENL is described as an immune reaction mediated by neutrophils, studies demonstrating the direct role of neut...

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Bibliographic Details
Main Authors: Isabella Forasteiro Tavares, Jessica Brandão dos Santos, Fabiana dos Santos Pacheco, Mariana Gandini, Rafael M. Mariante, Thais Fernanda Rodrigues, Anna Maria Sales, Milton Ozório Moraes, Euzenir Nunes Sarno, Veronica Schmitz
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Medicine
Subjects:
leprosy
Mycobacterium leprae
Erythema Nodosum Leprosum
neutrophilic degranulation
low-density neutrophils (LDNs)
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.711623/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.711623/full

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