Large Scale Production and Downstream Processing of Labyrinthopeptins from the Actinobacterium Actinomadura namibiensis

Large Scale Production and Downstream Processing of Labyrinthopeptins from the Actinobacterium Actinomadura namibiensis

A method was established for the production of 1.2-fold and 4.2-fold increased amounts of the antiviral and central nervous system-active lantipeptides, labyrinthopeptins A1 and A2, respectively, isolated from the actinobacterium Actinomadura namibiensis, to enable production in gram scale. We then...

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Bibliographic Details
Main Authors: Zeljka Rupcic, Stephan Hüttel, Steffen Bernecker, Sae Kanaki, Marc Stadler
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Bioengineering
Subjects:
anti-viral agents
bioprocess
central nervous system
lantibiotics
optimization production
reversed phase-high performance liquid chromatography
scale-up
Online Access:http://www.mdpi.com/2306-5354/5/2/42

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http://www.mdpi.com/2306-5354/5/2/42

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