Differential trafficking of oxidized LDL and oxidized LDL immune complexes in macrophages: impact on oxidative stress.

Oxidized low-density lipoproteins (oxLDL) and oxLDL-containing immune complexes (oxLDL-IC) contribute to formation of lipid-laden macrophages (foam cells). It has been shown that oxLDL-IC are considerably more efficient than oxLDL in induction of foam cell formation, inflammatory cytokines secretion...

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Main Authors: Mohammed M Al Gadban, Kent J Smith, Farzan Soodavar, Christabelle Piansay, Charlyne Chassereau, Waleed O Twal, Richard L Klein, Gabriel Virella, Maria F Lopes-Virella, Samar M Hammad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2932722?pdf=render