The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks

Summary: Regular endurance training improves muscle oxidative capacity and reduces the risk of age-related disorders. Understanding the molecular networks underlying this phenomenon is crucial. Here, by exploiting the power of computational modeling, we show that endurance training induces profound...

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Bibliographic Details
Main Authors: Kim Clarke, Sara Ricciardi, Tim Pearson, Izwan Bharudin, Peter K. Davidsen, Michela Bonomo, Daniela Brina, Alessandra Scagliola, Deborah M. Simpson, Robert J. Beynon, Farhat Khanim, John Ankers, Mark A. Sarzynski, Sujoy Ghosh, Addolorata Pisconti, Jan Rozman, Martin Hrabe de Angelis, Chris Bunce, Claire Stewart, Stuart Egginton, Mark Caddick, Malcolm Jackson, Claude Bouchard, Stefano Biffo, Francesco Falciani
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717314870