Fetal liver hematopoiesis: from development to delivery

Abstract Clinical transplants of hematopoietic stem cells (HSC) can provide a lifesaving therapy for many hematological diseases; however, therapeutic applications are hampered by donor availability. In vivo, HSC exist in a specified microenvironment called the niche. While most studies of the niche...

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Bibliographic Details
Main Authors: Kyle Lewis, Momoko Yoshimoto, Takanori Takebe
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13287-021-02189-w