Lipase-catalyzed Baeyer-Villiger Oxidation ofcellulose-derived Levoglucosenone into(S)-gamma-hydroxymethyl-□alpha,beta□-butenolide:Optimization by Response SurfaceMethodology

Lipase-catalyzed Baeyer-Villiger Oxidation ofcellulose-derived Levoglucosenone into(S)-gamma-hydroxymethyl-□alpha,beta□-butenolide:Optimization by Response SurfaceMethodology

Cellulose-derived levoglucosenone (LGO) has been efficiently converted into pure (S)-gamma-hydroxymethyl-alpha,beta-butenolide (HBO), a chemical platform suited for the synthesis of drugs, flavors and antiviral agents. This process involves two-steps: a lipase-catalyzed Baeyer-Villager oxidation of...

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Bibliographic Details
Main Authors: Andreia eTeixeira, Amandine eFlourat, Aurelien ePeru, Fanny eBrunissen, Florent eAllais
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Chemistry
Subjects:
Lipase
Baeyer-Villiger Biooxidation
Response Surface Methodology
Levoglucosenone
Enzymatic reaction
Reaction optimization
Online Access:http://journal.frontiersin.org/Journal/10.3389/fchem.2016.00016/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fchem.2016.00016/full

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