Cryo-EM structures of KdpFABC suggest a K+ transport mechanism via two inter-subunit half-channels

Cryo-EM structures of KdpFABC suggest a K+ transport mechanism via two inter-subunit half-channels

The P-type ATPase subunit KdpB of KdpFABC hydrolyzes ATP while K+ transport was assumed to occur through channel-like subunit KdpA. Here, the authors show two cryo-EM structures of KdpFABC which suggest a translocation pathway through two inter-subunit half-channels formed by KdpA and KdpB.

Bibliographic Details
Main Authors: C. Stock, L. Hielkema, I. Tascón, D. Wunnicke, G. T. Oostergetel, M. Azkargorta, C. Paulino, I. Hänelt
Format: Article
Language:English
Published: Nature Publishing Group 2018-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07319-2

Internet

https://doi.org/10.1038/s41467-018-07319-2

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