The Mitochondrial Hsp90 TRAP1 and Alzheimer’s Disease

Alzheimer’s Disease (AD) is the most common form of dementia, characterised by intra- and extracellular protein aggregation. In AD, the cellular protein quality control (PQC) system is derailed and fails to prevent the formation of these aggregates. Especially the mitochondrial paralogue of the cons...

Full description

Bibliographic Details
Main Authors: Françoise A. Dekker, Stefan G. D. Rüdiger
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.697913/full