Evaluation of G2677T/A polymorphism of MDR1 gene by polymerase chain reaction in Mazandaran province, Iran
The human MDR1 gene encodes for a P-glycoprotein (PGP), which acts as an efflux pump that transports a large variety of substrates from the inside of cells to the outside until protection against xenobiotics. The G2677T/A polymorphism in exon 21 is associated with PGP expression and function in huma...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Mazandaran University of Medical Sciences
2015-06-01
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Series: | Pharmaceutical and Biomedical Research |
Subjects: | |
Online Access: | http://pbr.mazums.ac.ir/browse.php?a_code=A-10-26-16&slc_lang=en&sid=1 |