ICGEC: a comparative method for measuring epigenetic conservation of genes via the integrated signal from multiple histone modifications between cell types

Abstract Background Histone post-translational modifications play crucial roles in epigenetic regulation of gene expression and are known to be associated with the phenotypic differences of different cell types. Therefore, it is of fundamental importance to dissect the genes and pathways involved in...

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Bibliographic Details
Main Authors: Jing Tang, Zefeng Wu, Yuhan Tian, Ruolin Yang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Genomics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12864-020-6771-1