Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes lymphangiogenesis through the Src/eNOS pathway in silicosis

Silicosis, a type of lung inflammation and fibrosis caused by long-term inhalation of SiO2 particles, lacks effective treatment currently. Based on the results of our previous animal experiments, in lungs of SiO2-induced silicosis rats, a large number of lymphatic vessels are generated in the early...

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Bibliographic Details
Main Authors: Jinsong Zhang, Jie Cui, Xinying Li, Xiaohui Hao, Lingli Guo, Hongli Wang, Heliang Liu
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321003687