Associations of the hypertension-related single nucleotide polymorphism rs11191548 with high-density lipoprotein cholesterol and leptin in Chinese children

Abstract Background The genome-wide association study has founded hypertension-related single nucleotide polymorphism (SNP) rs11191548 near CYP17A1 encoding a key enzyme involved in steroid metabolism, but the molecular mechanisms are not understood and the associations of the SNP with hypertension-...

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Bibliographic Details
Main Authors: Lijun Wu, Liwang Gao, Xiaoyuan Zhao, Meixian Zhang, Jianxin Wu, Jie Mi
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Medical Genetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12881-018-0523-y