TAT Modification of Alpha-Helical Anticancer Peptides to Improve Specificity and Efficacy.

HPRP-A1 is an amphipathic α-helical anticancer peptide (ACP) derived from the N-terminus of ribosomal protein L1 (RpL1) of Helicobacter pylori. In our previously study, HPRP-A1 has been reported that induced HeLa cell apoptosis in a caspase-dependent approach and involved both by the death receptor...

Full description

Bibliographic Details
Main Authors: Xueyu Hao, Qiuyan Yan, Jing Zhao, Wenren Wang, Yibing Huang, Yuxin Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4583266?pdf=render