Impact of NR1I2, adenosine triphosphate–binding cassette transporters genetic polymorphisms on the pharmacokinetics of ginsenoside compound K in healthy Chinese volunteers

Impact of NR1I2, adenosine triphosphate–binding cassette transporters genetic polymorphisms on the pharmacokinetics of ginsenoside compound K in healthy Chinese volunteers

Background: Ginsenoside compound K (CK) is a promising drug candidate for rheumatoid arthritis. This study examined the impact of polymorphisms in NR1I2, adenosine triphosphate–binding cassette (ABC) transporter genes on the pharmacokinetics of CK in healthy Chinese individuals. Methods: Forty-two t...

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Bibliographic Details
Main Authors: Luping Zhou, Lulu Chen, Yaqin Wang, Jie Huang, Guoping Yang, Zhirong Tan, Yicheng Wang, Jianwei Liao, Gan Zhou, Kai Hu, Zhenyu Li, Dongsheng Ouyang
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Journal of Ginseng Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1226845318300393

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http://www.sciencedirect.com/science/article/pii/S1226845318300393

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