Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y<sub>12</sub> Inhibition

Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y<sub>12</sub> Inhibition

There is evidence for the effects of platelet inhibition on innate immune activation. Circulating microRNAs (miRNAs) have been implicated as markers of platelet and leukocyte activation. In the present study, we assessed the effects of P2Y<sub>12</sub> inhibitors on platelet and leukocyt...

Full description

Bibliographic Details
Main Authors: Aitana Braza-Boïls, Temo Barwari, Clemens Gutmann, Mark R. Thomas, Heather M. Judge, Abhishek Joshi, Raimund Pechlaner, Manu Shankar-Hari, Ramzi A. Ajjan, Ian Sabroe, Robert F. Storey, Manuel Mayr
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Subjects:
biomarker
microRNA
antiplatelet therapy
sepsis
Online Access:https://www.mdpi.com/1422-0067/21/8/2897

Internet

https://www.mdpi.com/1422-0067/21/8/2897

Similar Items