Effect of interferon-γ on the fusion of mononuclear osteoclasts into bone-resorbing osteoclasts

Effect of interferon-γ on the fusion of mononuclear osteoclasts into bone-resorbing osteoclasts

Osteoclasts are multinucleated cells that are formed by the fusionof pre-fusion osteoclasts (pOCs). The fusion of pOCs isknown to be important for osteoclastic bone resorption. Here,we examined the effect of IFN-γ on the fusion of pOCs. IFN-γgreatly increased the fusion of pOCs in a dose-dependentma...

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Bibliographic Details
Main Authors: Jeung Woo Kim, Myeung Su Lee, Chang Hoon Lee, Ha Young Kim, Soo Uk Chae, Han Bok Kwak, Jaemin Oh
Format: Article
Language:English
Published: Korean Society for Biochemistry and Molecular Biology 2012-05-01
Series:BMB Reports
Subjects:
Fusion
Interferon
Osteoclasts
Online Access:http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS01JTVEMTIwNTI0MjAxM18lMjgyODEtMjg2JTI5Qk1CXzExLTI3Mi5wZGY=

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http://bmbreports.org/jbmb/pdf.php?data=MTMxMTA4MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS01JTVEMTIwNTI0MjAxM18lMjgyODEtMjg2JTI5Qk1CXzExLTI3Mi5wZGY=

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