Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder

Autoantibodies Against the Complement Regulator Factor H in the Serum of Patients With Neuromyelitis Optica Spectrum Disorder

Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune inflammatory disease of the central nervous system (CNS), characterized by pathogenic, complement-activating autoantibodies against the main water channel in the CNS, aquaporin 4 (AQP4). NMOSD is frequently associated with additional au...

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Bibliographic Details
Main Authors: Barbara Uzonyi, Zsóka Szabó, Eszter Trojnár, Satu Hyvärinen, Katalin Uray, Helle H. Nielsen, Anna Erdei, T. Sakari Jokiranta, Zoltán Prohászka, Zsolt Illes, Mihály Józsi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Immunology
Subjects:
aquaporin (AQP) 4
complement
factor H
neuromyelitis optica spectrum disorder
autoantibody
autoimmunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.660382/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.660382/full

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