A K+-selective CNG channel orchestrates Ca2+ signalling in zebrafish sperm

Calcium in the flagellum controls sperm navigation. In sperm of marine invertebrates and mammals, Ca2+ signalling has been intensely studied, whereas for fish little is known. In sea urchin sperm, a cyclic nucleotide-gated K+ channel (CNGK) mediates a cGMP-induced hyperpolarization that evokes Ca2+...

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Bibliographic Details
Main Authors: Sylvia Fechner, Luis Alvarez, Wolfgang Bönigk, Astrid Müller, Thomas K Berger, Rene Pascal, Christian Trötschel, Ansgar Poetsch, Gabriel Stölting, Kellee R Siegfried, Elisabeth Kremmer, Reinhard Seifert, U Benjamin Kaupp
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/07624