Saccadic eye movement characteristics in adult Niemann-Pick Type C disease: relationships with disease severity and brain structural measures.

Saccadic eye movement characteristics in adult Niemann-Pick Type C disease: relationships with disease severity and brain structural measures.

Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC. Neuropathology is widespread in NPC, however, and could...

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Bibliographic Details
Main Authors: Larry A Abel, Elizabeth A Bowman, Dennis Velakoulis, Michael C Fahey, Patricia Desmond, Matthew D Macfarlane, Jeffrey Chee Leong Looi, Christopher L Adamson, Mark Walterfang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511378?pdf=render

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http://europepmc.org/articles/PMC3511378?pdf=render

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