Extract of Paecilomyces hepiali mycelia induces lipolysis through PKA-mediated phosphorylation of hormone-sensitive lipase and ERK-mediated downregulation of perilipin in 3T3-L1 adipocytes

Extract of Paecilomyces hepiali mycelia induces lipolysis through PKA-mediated phosphorylation of hormone-sensitive lipase and ERK-mediated downregulation of perilipin in 3T3-L1 adipocytes

Abstract Background Cordyceps sinensis has been used for centuries in China as one of the most valued herbal medicine and tonic food. Paecilomyces hepiali, a fungal strain isolated from natural C. sinensis, has been used widely as a substitute of C. sinensis in medicine and health food. P. hepiali h...

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Bibliographic Details
Main Authors: Mei Ge, Rui Guo, Hai-xia Lou, Wen Zhang
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Complementary and Alternative Medicine
Subjects:
Paecilomyces hepiali
3T3-L1 adipocyte
Lipolytic effect
PKA
ERK
Online Access:http://link.springer.com/article/10.1186/s12906-018-2389-0

Internet

http://link.springer.com/article/10.1186/s12906-018-2389-0

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