Cisplatin Targeting of Bacterial Ribosomal RNA Hairpins
Cisplatin is a clinically important chemotherapeutic agent known to target purine bases in nucleic acids. In addition to major deoxyribonucleic acid (DNA) intrastrand cross-links, cisplatin also forms stable adducts with many types of ribonucleic acid (RNA) including siRNA, spliceosomal RNAs, tRNA,...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/16/9/21392 |