PI3k and Stat3: Oncogenes that are Required for Gap Junctional, Intercellular Communication

Gap junctional, intercellular communication (GJIC) is interrupted in cells transformed by oncogenes such as activated Src. The Src effector, Ras, is required for this effect, so that Ras inhibition restores GJIC in Src-transformed cells. Interestingly, the inhibition of the Src effector phosphatidyl...

Full description

Bibliographic Details
Main Authors: Mulu Geletu, Zaid Taha, Patrick T. Gunning, Leda Raptis
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Cancers
Subjects:
Src
Online Access:https://www.mdpi.com/2072-6694/11/2/167