Sustained release biodegradable solid lipid microparticles: Formulation, evaluation and statistical optimization by response surface methodology
For preparing nebivolol loaded solid lipid microparticles (SLMs) by the solvent evaporation microencapsulation process from carnauba wax and glyceryl monostearate, central composite design was used to study the impact of independent variables on yield (Y1), entrapment efficiency (Y2) and drug releas...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2017-12-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.1515/acph-2017-0034 |