Interactions of Alginate-Deferoxamine Conjugates With Blood Components and Their Antioxidation in the Hemoglobin Oxidation Model

Interactions of Alginate-Deferoxamine Conjugates With Blood Components and Their Antioxidation in the Hemoglobin Oxidation Model

While deferoxamine (DFO) has long been used as an FDA-approved iron chelator, its proangiogenesis ability attracts increasing number of research interests. To address its drawbacks such as short plasma half-life and toxicity, polymeric conjugated strategy has been proposed and shown superiority. Owi...

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Bibliographic Details
Main Authors: Tong Sun, Xi Guo, Rui Zhong, Chengwei Wang, Hao Liu, Hao Li, Lu Ma, Junwen Guan, Chao You, Meng Tian
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
deferoxamine
blood components
antioxidation
alginate
conjugates
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00053/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00053/full

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