Novel Nonphosphorylated Serine 9/21 GSK3β/a Antibodies: Expanding the Toolkit for Studying GSK3 Regulation

Glycogen synthase kinase 3 (GSK3) and are serine/threonine kinases involved in many biological processes. A primary mechanism of GSK3 activity regulation is phosphorylation of N-terminal serine (S) residues (S9 in GSK3b, S21 in GSK3a). Phosphorylation is inhibitory to GSK3 kinase activity because...

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Bibliographic Details
Main Authors: Tessa Grabinski, Nicholas M Kanaan
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00123/full