DNA isolation method is a source of global DNA methylation variability measured with LUMA. Experimental analysis and a systematic review.

DNA isolation method is a source of global DNA methylation variability measured with LUMA. Experimental analysis and a systematic review.

In DNA methylation, methyl groups are covalently bound to CpG dinucleotides. However, the assumption that methyl groups are not lost during routine DNA extraction has not been empirically tested. To avoid nonbiological associations in DNA methylation studies, it is essential to account for potential...

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Bibliographic Details
Main Authors: Carolina Soriano-Tárraga, Jordi Jiménez-Conde, Eva Giralt-Steinhauer, Angel Ois, Ana Rodríguez-Campello, Elisa Cuadrado-Godia, Israel Fernández-Cadenas, Joan Montaner, Gavin Lucas, Roberto Elosua, Jaume Roquer, GeneStroke “The Spanish Stroke Genetics Consortium”
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3621987?pdf=render

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http://europepmc.org/articles/PMC3621987?pdf=render

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