1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB

1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB

1,8-Cineole (eucalyptol), a monoterpene, has been widely reported for the anti-inflammatory effects. Our previous data confirmed that 1,8-cineole ameliorated the inflammatory phenotype of human umbilical vein endothelial cells (HUVECs) by mediating NF-κB expression in vitro. At present, we investiga...

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Bibliographic Details
Main Authors: Ke-Gang Linghu, Guo-Ping Wu, Ling-Yun Fu, Hong Yang, Hai-Zhi Li, Yan Chen, Hua Yu, Ling Tao, Xiang-Chun Shen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pharmacology
Subjects:
1
8-cineole
human umbilical vein endothelial cell
lipopolysaccharide
NF-κB
PPAR-γ
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00178/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2019.00178/full

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