Orexins as Novel Therapeutic Targets in Inflammatory and Neurodegenerative Diseases

Orexins as Novel Therapeutic Targets in Inflammatory and Neurodegenerative Diseases

Orexins [orexin-A (OXA) and orexin-B (OXB)] are two isoforms of neuropeptides produced by the hypothalamus. The main biological actions of orexins, focused on the central nervous system, are to control the sleep/wake process, appetite and feeding, energy homeostasis, drug addiction, and cognitive pr...

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Bibliographic Details
Main Authors: Alain Couvineau, Thierry Voisin, Pascal Nicole, Valérie Gratio, Catalina Abad, Yossan-Var Tan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Endocrinology
Subjects:
orexins
neuropeptides
GPCR
inflammation
neuroprotection
gastroenterology
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00709/full

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https://www.frontiersin.org/article/10.3389/fendo.2019.00709/full

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