Discovery of novel helix binding sites at protein-protein interfaces
Protein-protein interactions (PPIs) play a key role in numerous biological processes. Many efforts have been undertaken to develop PPI modulators for therapeutic applications; however, to date, most of the peptide binders designed to target PPIs are derived from native binding helices or using the n...
Main Authors: | Wei Yang, Xiangyu Sun, Changsheng Zhang, Luhua Lai |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-01-01
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Series: | Computational and Structural Biotechnology Journal |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037019302053 |
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