Müller Cell-Derived PEDF Mediates Neuroprotection via STAT3 Activation

Müller Cell-Derived PEDF Mediates Neuroprotection via STAT3 Activation

Background/ Aims: This study was performed to reveal signaling pathways exploited by pigment epithelium-derived factor (PEDF) derived from retinal (glial) Müller cells to protect retinal ganglion cells (RGCs) from cell death. Methods: The survival of RGCs was determined in the presence of conditione...

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Bibliographic Details
Main Authors: Wolfram Eichler, Helena Savković-Cvijić, Susanne Bürger, Mike Beck, Manuela Schmidt, Peter Wiedemann, Andreas Reichenbach, Jan Darius Unterlauft
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Neuroprotection
Retinal ganglion cells
Müller cells
PEDF
Online Access:https://www.karger.com/Article/FullText/485537

Internet

https://www.karger.com/Article/FullText/485537

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