Identifying human disease genes through cross-species gene mapping of evolutionary conserved processes.
Understanding complex networks that modulate development in humans is hampered by genetic and phenotypic heterogeneity within and between populations. Here we present a method that exploits natural variation in highly diverse mouse genetic reference panels in which genetic and environmental factors...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-05-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3087714?pdf=render |